@article {826, title = {Structural connectivity alterations in chronic and episodic migraine: A diffusion magnetic resonance imaging connectomics study}, journal = {Cephalalgia}, volume = {40}, year = {2020}, pages = {367-383}, abstract = {

OBJECTIVE:

To identify possible structural connectivity alterations in patients with episodic and chronic migraine using magnetic resonance imaging data.

METHODS:

Fifty-four episodic migraine, 56 chronic migraine patients and 50 controls underwent T1-weighted and diffusion-weighted magnetic resonance imaging acquisitions. Number of streamlines (trajectories of estimated fiber-tracts), mean fractional anisotropy, axial diffusivity and radial diffusivity were the connectome measures. Correlation analysis between connectome measures and duration and frequency of migraine was performed.

RESULTS:

Higher and lower number of streamlines were found in connections involving regions like the superior frontal gyrus when comparing episodic and chronic migraineurs with controls (p \< .05 false discovery rate). Between the left caudal anterior cingulate and right superior frontal gyri, more streamlines were found in chronic compared to episodic migraine. Higher and lower fractional anisotropy, axial diffusivity, and radial diffusivity were found between migraine groups and controls in connections involving regions like the hippocampus. Lower radial diffusivity and axial diffusivity were found in chronic compared to episodic migraine in connections involving regions like the putamen. In chronic migraine, duration of migraine was positively correlated with fractional anisotropy and axial diffusivity.

CONCLUSIONS:

Structural strengthening of connections involving subcortical regions associated with pain processing and weakening in connections involving cortical regions associated with hyperexcitability may coexist in migraine

}, keywords = {Magnetic resonance imaging (MRI), Migraine, chronic migraine, connectomics, diffusion-weighted imaging, tractography}, doi = {10.1177/0333102419885392}, author = {{\'A}lvaro Planchuelo-G{\'o}mez and Garc{\'\i}a-Azor{\'\i}n, David and {\'A}ngel L. Guerrero and Santiago Aja-Fern{\'a}ndez and Rodr{\'\i}guez, Margarita and Rodrigo de Luis-Garc{\'\i}a} } @conference {815, title = {Single-Shell Return-to-the-Origin Probability Diffusion Mri Measure Under a Non-Stationary Rician Distributed Noise}, booktitle = {2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019)}, year = {2019}, publisher = {IEEE}, organization = {IEEE}, author = {Tomasz Pieciak and Bogusz, Fabian and Antonio Trist{\'a}n-Vega and Rodrigo de Luis-Garc{\'\i}a and Santiago Aja-Fern{\'a}ndez} } @article {781, title = {Scalar diffusion-MRI measures invariant to acquisition parameters: A first step towards imaging biomarkers}, journal = {Magnetic Resonance Imaging}, volume = {54}, year = {2018}, month = {2018}, pages = {194 - 213}, issn = {0730-725X}, doi = {https://doi.org/10.1016/j.mri.2018.03.001}, url = {http://www.sciencedirect.com/science/article/pii/S0730725X18300262}, author = {Santiago Aja-Fern{\'a}ndez and Tomasz Pieciak and Antonio Trist{\'a}n-Vega and Gonzalo Vegas-S{\'a}nchez-Ferrero and Vicente Molina and Rodrigo de Luis-Garc{\'\i}a} } @inbook {de2009segmentation, title = {Segmentation of tensor fields: Recent advances and perspectives}, booktitle = {Tensors in Image Processing and Computer Vision}, year = {2009}, pages = {35{\textendash}58}, publisher = {Springer}, organization = {Springer}, author = {Rodrigo de Luis-Garc{\'\i}a and Carlos Alberola-Lopez and Carl-Fredik Westin} } @proceedings {sosa2008strain, title = {Strain index: a new visualizing parameter for US elastography}, year = {2008}, pages = {69200W{\textendash}69200W}, publisher = {International Society for Optics and Photonics}, author = {Dario Sosa-Cabrera and Rodrigo de Luis-Garc{\'\i}a and Antonio Trist{\'a}n-Vega and Carlos Alberola-Lopez and Juan Ruiz-Alzola} } @proceedings {sosa2008strain, title = {Strain index: a new visualizing parameter for US elastography}, volume = {6920}, year = {2008}, pages = {6920}, publisher = {International Society for Optical Engineering; 1999}, author = {Dario Sosa-Cabrera and Rodrigo de Luis-Garc{\'\i}a and Antonio Trist{\'a}n-Vega and Carlos Alberola-Lopez and Juan Ruiz-Alzola} }