An automatic classification system into either malignant or benign microcalcification from mammograms is a helpful tool in breast cancer diagnosis. From a set of extracted features, a classifying method using neural networks can provide a probability estimation that can help the radiologist in his diagnosis. With this objective in mind, this paper proposes a feature selection algorithm from a massive number of features based on a statistical distance method in conjunction with a genetic algorithm (GA). The use of a statistical distance as optimality criterion was improved with genetic algorithms for selecting an appropriate subset of features, thus making this algorithm capable of performing feature selection from a massive set of initial features. Additionally, it provides a criterion to select an appropriate number of features to be employed. Experimental work was performed using Generalized Softmax Perceptrons (GSP), trained with a Strict Sense Bayesian cost function for direct probability estimation, as microcalcification classifiers. A Posterior Probability Model Selection (PPMS) algorithm was employed to determine the network complexity. Results showed that this algorithm converges into a subset of features which has a good classification rate and Area Under Curve (AUC) of the Receiver Operating Curve (ROC). {\^A}{\textcopyright} Springer-Verlag Berlin Heidelberg 2007.

}, keywords = {Breast cancer, Diagnosis, Feature extraction, Genetic algorithms, Mammography, Microcalcification classification, Network complexity, Neural network classifiers, Neural networks, Tumors}, isbn = {9783540742715}, issn = {03029743}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-38149142403\&partnerID=40\&md5=ef139db3a0e5d603c4f721316abdcf2c}, author = {G V Sanchez-Ferrero and J I Arribas} } @conference {415, title = {Neural network fusion strategies for identifying breast masses}, booktitle = {IEEE International Conference on Neural Networks - Conference Proceedings}, year = {2004}, address = {Budapest}, abstract = {In this work, we introduce the Perceptron Average neural network fusion strategy and implemented a number of other fusion strategies to identify breast masses in mammograms as malignant or benign with both balanced and imbalanced input features. We numerically compare various fixed and trained fusion rules, i.e., the Majority Vote, Simple Average, Weighted Average, and Perceptron Average, when applying them to a binary statistical pattern recognition problem. To judge from the experimental results, the Weighted Average approach outperforms the other fusion strategies with balanced input features, while the Perceptron Average is superior and achieves the goals with lowest standard deviation with imbalanced ensembles. We concretely analyze the results of above fusion strategies, state the advantages of fusing the component networks, and provide our particular broad sense perspective about information fusion in neural networks.

}, keywords = {Biological organs, Breast cancers, Component neural networks (CNN), Image segmentation, Information fusions, Learning algorithms, Linear systems, Mammography, Mathematical models, Multilayer neural networks, Pattern recognition, Posterior probabilities, Tumors}, isbn = {0780383591}, doi = {10.1109/IJCNN.2004.1381010}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-10844231826\&partnerID=40\&md5=2be794a5832413fed34152d61dd49388}, author = {Y Wu and J He and Y Man and J I Arribas} }