News

Alternative Anisotropy Measure for diffusion MRI

[14 Dec 2020]

A new paper entitled Apparent propagator anisotropy from single‐shell diffusion MRI acquisitions has been published in Magnetic Resonance in Medicine. The work is written by members of the LPI (Santiago Aja-Fernández, Antonio Tristán-Vega) in collaboration with CUBRIC, University of Cardiff, UK (D.K. Jones). In the work, we propose a method to effectively calculate apparent Propagator Anisotropy (APA) from single shell diffusion MRI. The method avoids the calculation of the whole EAP by assuming the diffusion anisotropy is roughly independent from the radial direction. With such an assumption we achieve closed-form expressions for the measures using information from one single shell. At the same time, the closed forms provided make the method computationally efficient and robust.

Gray matter morphometry alterations in migraine

[23 Nov 2020]

A paper about the assessment of gray matter morphometry parameters in migraine patients, Gray Matter Structural Alterations in Chronic and Episodic Migraine: A Morphometric Magnetic Resonance Imaging Study, has been published in Pain Medicine. This article has been written by Álvaro Planchuelo-Gómez, Santiago Aja-Fernández and Rodrigo de Luis-García, in collaboration with the Headache Unit and the Department of Radiology of the Clinical Hospital of Valladolid. The findings of this research suggest that there are widespread gray matter alterations in migraine. Chronic migraine would be a distinct entity with respect to a high frequency episodic migraine and the surface area would be a proper biomarker to identify it. The results of this study suggest that the pattern of differences between healthy controls and episodic migraine patients is qualitatively different from that occurring between episodic and chronic migraine patients. The article is available here: https://doi.org/10.1093/pm/pnaa271

LPI in ESMRMB 2020

[01 Nov 2020]

Alejandro Godino-Moya has recieved the Certificate of Merit Award in the ESMRMB 2020 Congress, held online between 30th september and 2nd October 2020, for his poster "Combination of AlignedSENSE and groupwise motion-compensated compressed sense for cardiac cine MRI reconstruction".

Prof. Carlos Alberola-López have also taken part in the Radiomics scientific session of the ESMRMB 2020 with a talk entitled "Synthetic Imaging for Quantitative MRI".

New dMRI methodology uncovers additional alterations in migraine

[10 Nov 2020]

AMURA (https://www.lpi.tel.uva.es/AMURA), the new tool developed by LPI members, has been used to compare diffusion measures in patients with episodic and chronic migraine and healthy controls using clinical routine diffusion MRI acquisition parameters. Using AMURA, additional statistically significant differences were found with respect to the diffusion tensor imaging (DTI) descriptors. This article demonstrates that AMURA can provide additional results with respect to DTI to uncover white matter alterations in migraine, even in suboptimal conditions for the tool with a single low b-value.
The new paper, entitled "Alternative Microstructural Measures to Complement Diffusion Tensor Imaging in Migraine Studies with Standard MRI Acquisition", has been published in Brain Sciences. The article is available here (Open Access): https://doi.org/10.3390/brainsci10100711

LPI research on COVID-19

[25 May 2020]

The first LPI article about the psychological impact of the COVID-19 confinement has been published. This article has been made in collaboration with the Department of Psychology of the University of Valladolid. The main finding was that students from Arts & Humanities and Social Sciences and Law areas showed higher psychological impact, especially compared to the students from the Engineering & Architecture field (click on the title of the article for more highlights). The article is freely available until 11 July in the following link: https://doi.org/10.1016/j.psychres.2020.113108

New dMRI methodology to calculate q-space measures

[11 Mar 2020]

A new paper entitled Micro-structure diffusion scalar measures from reduced MRI acquisitions has been published in PLOS ONE. The work is written by member of the LPI (Santiago Aja-Fernández, Rodrigo de Luis-García, Antonio Tristán-Vega)  in collaboration with reserachers from AGH University of Science and Technology, Krakow, Poland (Tomasz Pieciak) and CUBRIC, University of Cardiff, UK Maryam Afzali, Malwina Molendowska). In the work, we propose a method to effectively calculate apparent RTOP, RTPP, and RTAP from single shell diffusion MRI. The method achieves closed-form expressions and a computationally efficient and robust implementation. Methods are implemented in MATLAB and they will be publicly release soon. We can submitted them no upon request.  [Link to paper]

White matter changes in migraine

[07 Jan 2020]

A new paper, White matter changes in chronic and episodic migraine: a diffusion tensor imaging study, written by Álvaro Planchuelo-Gómez, Santiago Aja-Fernández and Rodrigo de Luis-García, in colaboration with the Headache Unit and the Deparment of Radiology of the Clinical Hospital of Valladolid, has been published in the Journal of Headache and Pain. In this article, global white matter differences between chronic and episodic migraine have been found for the first time using Diffusion Tensor Imaging (DTI) measures and Tract-Based Spatial Statistics (TBSS). Our findings suggest axonal integrity impairment in the first months of chronic migraine, with respect to episodic migraine, and a posterior set of maladaptive white matter plastic changes in chronic migraine.

LPI member interviewed

[07 Jan 2020]

Álvaro Planchuelo-Gómez and Dr. David García-Azorín, from the Headache Unit of the Clinical Hospital of Valladolid, have been interviewed by the International Headache Society. Following the article Structural connectivity alterations in chronic and episodic migraine: A diffusion magnetic resonance imaging connectomics study, they talked about the main findings of the article, future lines of research, implications for migraine patients and research communities interested in the paper.

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